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Glutamine (abbreviated as Gln or Q) is one of the 20 amino acids encoded by the standard genetic code. Its side chain is an amide formed by replacing the side-chain hydroxyl of glutamic acid with an amine functional group wedding hair. It can therefore be considered the amide of glutamic acid. Its codons are CAA and CAG. In human blood glutamine is the most abundant free amino acid with a concentration of about 500-900 µmol/l. Glutamine is synthetized by the enzyme glutamine synthetase from glutamate and ammonia. The most relevant glutamine producing organ is the muscle mass accounting for about 90% of all glutamine synthesized. To minor parts glutamine is released by the lung and the brain.[wedding cake toppers] Although the liver is capable of relevant glutamine synthesis, its role in glutamine metabolism is more regulatory than producing, since the liver takes up large amounts of glutamine derived from gut. In catabolic states of injury and illness, glutamine becomes conditionally-essential (requiring intake from food or supplements). Glutamine has been studied extensively over the past 10–15 years and has been shown to be useful in treatment of serious illnesses, injury, trauma, burns, and treatment related side-effects of cancer as well as in wound healing for postoperative patients.[bridal shower gifts] Glutamine is also marketed as a supplement used for muscle growth in weightlifting, bodybuilding, endurance, and other sports. In biological research, L-glutamine is commonly added to the media in cell culture. |
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